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An Animal as opposed to a Human - the Anti Christ    
When a man is separated from God he manifests as an intelligent Amimal.   He is effectively a brute Beast.   
But these, as natural brute beasts, made to be taken and destroyed, speak evil of the things that they understand not; and shall utterly perish in their own corruption;
Shallow knowledge of the scriptures leads to misinterpretation and imbalance in its application.     Spiritual wisdom comes by spiritual revelation of the Word.     Carnal Minded people do not grasp spiritual Truth and so speak evil against it.     

I believe this whole passage is the Holy Spirit telling us to respect all who preach and teach Christ Jesus, being careful not to undermine or discourage.

But these speak evil of those things which they know not: but what they know naturally, as brute beasts, in those things they corrupt themselves.
Those who are not In Christ are Carnal Minded servants of the flesh.

The Beast of Revelation, the Anti Christ, is referenced in the following:
Let no man deceive you by any means: for that day shall not come, except there come a falling away first, and that man of sin be revealed, the son of perdition;
Do not be deceived!     This warning is always associated with the End Times.     

'That day' is the Day Of The Lord Jesus Christ.     

The Falling Away will happen as a result of
    false teaching leading to false expectations
    deceitfulness of sin and its legitimization
    turning from the Word and fellowship in the Holy Spirit.     

The 'man of sin' is the beast, the antichrist.     
The revelation of the beast is accompanied by
    a complete disavowal of sin
    denial of Jesus Christ
    glorification of humanity.

See .    .    .   .