We are most familiar with poisons that enter the body through the mouth or skin.   But our ears and eyes are also susceptible to poison.   What we hear affects what we think.   What we sees affects what we think.   As we think in our hearts, so are we Pro 23:7 .   

The fact of the matter is that man was designed for truth, beauty and life.   Our Creator is Truth, Beauty and Life and we were designed to be like Him and fellowship with Him on that commonality.   

Anything that is not Truth, that is not Beautiful, that does not promote Life is poison.   
Adam and Eve chose poison in taking of the forbidden fruit and mankind has suffered since.   In Christ Jesus we have newness of life in which we are to exist once again in fellowship with our Creator.   

Experimenting with poison is dangerously foolish.   How much poison can you take without it harming you?   None.   There is always damage to Truth, Beauty and Life when poison enters us.   Can we survive it?   Yes, by the Grace of God, but we inevitably suffer loss.   

Poison: In the context of biology, poisons are substances that can cause disturbances to organisms,[1] usually by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by an organism.   Legally and in hazardous chemical labeling, poisons are especially toxic substances; less toxic substances are labeled "harmful", "irritant", or not labeled at all.    - Wikipedia