Knowledge of man's thoughts brings the illusion of happiness and eternal death.
All men come to realize this when they draw their last breath.
The Holy Spirit Of Christ Jesus is the Spirit Of Truth.
Many people know about Jesus. Some even know what He said and did. But knowledge about Christ Jesus is not the knowledge of the Truth that this verse is speaking of.
Knowledge of the Truth comes by faith in the Word of the Lord concerning Jesus. That faith produces Eternal Life in the believer on the authority of the Lord`s Word Rom 10:17 Rom 10:10.
In the secular realm, knowledge is the end all. Disciplines are contrived in which knowledge is pursued. However, without the correct assumptions, a discipline or thread of knowledge is merely an intellectual game having no connection at all to Truth.
The acknowledgement of the Creator must be assumption number one. Otherwise, the pursuit is the pursuit of a fool. Pro 1:7 Pro 9:10 Psm 14:1 Psm 53:1 Rom 1:21
To know the Holy Spirit, the Spirit Of Christ Jesus is for Him to abide in us and for us to abide in Him.
The purpose of Jesus coming is for us to receive His Holy Spirit and become One with Him. Mat 3:11
In receiving the Gospel of Grace Through Faith we are Born Again of the Word and His Holy Spirit. This means that we already have Eternal Life through Jesus Christ our Lord Rom 6:23.
Eternity in the Spirit Realm is already our state of existence Joh 11:26. So walk in Newness Of Life Gal 5:25.
Every human being is born with a sense that there is a Supreme Being.
On what basis does a person decide to reject the notion of God? Rebellion . Every other explanation they offer is just cover for the fact that they hate God and wish that He did not exist. Such are children of Satan - the first rebel.
This is why repentance is needed to come to God in Christ Jesus. One must see themselves as a rebel in opposition to the very One who created them and loved them enough to die for their reconciliation to Himself.
Those who persist in their rebellion against God spiral down eventually getting to the point where they are unreachable by the Truth.
Such end up with Reprobate Minds because they knowingly and willfully reject the Truth, Jesus Christ.
There are two major results of this: ➛ they do things which are self-destructive ➛ the Holy Spirit ceases to draw them.